Cell-Logic EnduraCell Plus

• Stimulates cellular antioxidant defences within the body
• Broccoli sprouts may activate key enzymes in liver detoxification
• Scientific research indicates that selenium supports antioxidant activity in the body

Broccoli sprouts when produced according to Cell-Logic’s proprietary Australian technology are a highly-concentrated source of Broccoli phytonutrients. The benefits of Broccoli in the human diet are well-known.

EnduraCell Plus® combines 100% Whole Broccoli Sprout powder with a natural source of selen-ium. Selenium is a trace element which is associated with the production of cell-protective com-pounds activated by broccoli phytonutrients.

EnduraCell Plus® does not contain goitrogens or significant levels of Vitamin K.

Application

Adults: Take 1– 3 capsules twice daily or as directed by your Health Care Practitioner

Warnings

This product contains selenium which is toxic in high doses. For adults, a daily dose of 150 mi-crograms of selenium from dietary supplements should not be exceeded.

Do not exceed 6 capsules daily.

Store below 30°C away from light and moisture.

Very occasionally, gastro-intestinal adverse effects have been reported, and include nausea, gastro-abdominal discomfort and diarrhoea. Limited data available seem to indicate that such effects are limited to certain pre-existing gastro-intestinal conditions, in particular, those with dysbiosis. However, it has been observed that for those affected, the dose can be managed in a manner whereby the symptoms disappear and may not recur even after the consumption of larger doses.

Evidence

Li D et al. Synergy between broccoli sprout extract and selenium in the upregulation of thioredoxin reductase in human hepatocytes Food Chemistry 110 (2008) 193–198

Lee J-M, Johnson JA. An Important Role of Nrf2-ARE Pathway in the Cellular Defense Mechanism Journal of Biochemistry and Molecular Biology 2004 ; 37(2):139-143

Fahey JW, Talalay P. Antioxidant Functions of Sulforaphane: a Potent Inducer of Phase II Detoxication Enzymes. Food and Chemical Toxicology. 1999; 37:973-979

Fahey JW, Kensler TW. Role of dietary supplements/nutraceuticals in chemoprevention through induction of cytoprotective enzymes. Chem Res Toxicol. 2007 Apr;20(4):572-6.

Yeh C-T, Yen G-C. Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells. Carcinogenesis 2005;26 (12) ;2138–2148

Jeong W-S et al. Modulatory Properties of Various Natural Chemopreventive Agents on the Activation of NF-κB Signaling Pathway. Pharmaceutical Research. 2004;21(4): 661-670.

Innmorato NG et al. The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation. The Journal of Immunology 2008;181:680 – 689.

Wu L, Juurlink B The impaired glutathione system and its up-regulation by sulforaphane in vascular smooth muscle cells from spontaneously hypertensive rats. Journal of Hypertension 2001, 19:181-1825

Cramer J, Jeffery EH. Sulforaphane Absorption and Excretion Following Ingestion of a Semi-Purified Broccoli Powder Rich in Glucoraphanin and Broccoli Sprouts in Healthy Men.2011; Nutrition and Cancer, 63(2), 196–201

Halliwell B Free radicals and antioxidants – quo vadis? Trends in Pharmacological Sciences 2011: 32(3):125-130.

Kensler TW et al. Translational Strategies for cancer prevention in liver. Nature Reviews Cancer 3, 321-329 (May 2003)

2001 Steinkellner H et al. Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens. Mutation Research 480–481 (2001) 285–297.

Nutritional Information